Effects of Morphine and Genistein Injections on a Few Histological and Biochemical Liver Characteristics in White Male Laboratory Mice

Abstract

The therapeutic value of genistein as an antioxidant and anti-inflammatory in reducing the negative effects of morphine was examined in this study. Methods: Four groups of 48 male laboratory rats were established. Each group had twelve mice. The control group received a 0.1 M injection of sterile saline. The morphine group received an injection of morphine at a dose of 20 mg/kg; The genistein group received an injection of genistein at a dose of 25 mg/kg; The morphine and genistein group received an injection of morphine at a dose of 20 mg/kg for 15 days, followed by 15 days of receiving an injection of genistein. Rats were separated into three periods and given a subperitoneal injection once a day (five, ten and fifteen days of injection).