Autoimmune Diseases (lupus Erythematous)

Abstract

Lupus erythematous is an autoimmune disease, which means that the immune system erroneously acts against its own healthy tissues. It usually follows a chronic course and hence can also be termed as a chronic disease. It may involve only a single organ, but in its due course, it usually involves multiple organs of the body. There are various types of rashes in systemic lupus erythematosus (SLE), the butterfly‐like rash being the most famous. Up to now, many classifications of lupus have been given, but the classification into the discoid lupus and the disseminated lupus is being most widely accepted. From the time of Hippocrates, it was assumed to be present, and after many research studies, it is still a dreaded disease. Females are more affected than males by this disease. In the past, the survival rate of SLE was very poor. Now the survival rate has increased, thanks to the newer drugs and other strategies taken against this disease. The main causes of death from SLE were renal disease, neoplasm, CVD, cerebrovascular disease, respiratory disease and infection. It has been found that various genes cause the disease. In a small fraction of patients, the disease may be attributed to a single gene. But majority of the patients with this disease have multiple genes