PROBLEMS OF RESTENOSIS IN THE CORONARY ARTERIES AFTER PERCUTANEOUS CORONARY INTERVENTIONS DURING IMPLANTATION OF METAL OR DRUG-COATED STENTS, DEPENDING ON CLINICAL DATA AND RISK FACTORS

Abstract

To determine the difference between two types of stents: without and with a drug coating in the development of restenosis in the late stages after percutaneous coronary interventions (PCI), based on the initial clinical data and cardiovascular risk factors. The analysis included 32 patients with coronary artery disease: with holometallic stents (baremetal-stents – BMS) (n=15) and drug-coated stents (drug–elutingstents - DES) (n=17), subject to repeated coronary angiography performed according to clinical indications. All patients received appropriate antiplatelet and hypolipidemic therapy. During the indexPCI period, the group of DES patients, compared with the BMS group, was characterized by a significantly higher frequency of initial adverse signs, such as diabetes mellitus, smoker status, ACS. During the follow-up period, CAH in the DES group was less frequent than in the BMS group: restenoses were detected, repeated PCI was performed. The dynamics in risk factors during the follow-up period differed little between the groups.With follow-up periods extended to 2 years, taking into account the initial clinical data and SSR indicators, the effectiveness and validity of the use of drug-coated stents in comparison with uncoated stents is confirmed