IMMUNO-INFLAMMATORY MARKERS ASSOCIATED WITH LEFT VENTRICULAR REMODELING IN ISCHEMIC HEART DISEASE

Abstract

The article explores endothelial damage factors in arterial hypertension and ischemic heart disease, forming a cardiovascular syntropy. The cytokines considered as markers of endothelial dysfunction include IGF-I, VEGF, TGF-β1, and serum procalcitonin. The study found that patients with elevated VEGF levels have a high risk of developing and progressing cardiovascular pathology—particularly myocardial fibrosis and hypertrophy—against the background of arterial hypertension, regardless of its severity.