THE SIGNIFICANCE OF SOME BIOMARKERS OF NEUROINFLAMMATION AND ANGIOGENESIS IN STROKES

Abstract

In the recent past, the possibility of neurogenesis in the adult nervous system was denied. It has now been proven that neurogenesis continues throughout a person's life in 2 different areas of the intact brain - the subventricular zone of the lateral ventricles and the subgranular zone in the dentate gyrus of the hippocampus. Some authors also consider these areas as a single neurogenic zone [23]. Neurogenesis is a multistage process of formation of new neurons, astrocytes, oligodendrocytes in the CNS from neuronal stem cells (NSCs), including the proliferation of endogenous NSCs, their migration and differentiation into mature functional neurons. This process underlies the adaptive function of the brain and provides neuroplasticity, which is expressed in the structural and functional reorganization of neural networks. Stroke stimulates neurogenesis in the brain