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THE ROLE OF HYPOXIA-INDUCIBLE FACTOR HIF-1α IN THE PATHOGENESIS OF INTRAPARTUM FETAL DEATH IN PREECLAMPSIA

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dc.contributor.authorJabborova Munisxon Abdubanon qizi
dc.date.accessioned2026-01-12T20:33:01Z
dc.date.issued2026-01-12
dc.description.abstractThe purpose of this study was to investigate the role of hypoxia-inducible factor HIF-1α in the formation of fetoplacental insufficiency and the development of intrapartum fetal death in preeclampsia. The study included analysis of molecular genetic data in conjunction with Doppler measurements of fetoplacental blood flow. The findings established that HIF-1α hyperexpression is associated with endothelial cell apoptosis, reduced angiogenesis, and critical abnormalities in Doppler indices that precede acute intrapartum fetal hypoxia in preeclampsia.
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dc.identifier.urihttps://webofjournals.com/index.php/5/article/view/5818
dc.identifier.urihttps://asianeducationindex.com/handle/123456789/110641
dc.language.isoeng
dc.publisherWeb of Journals Publishing
dc.relationhttps://webofjournals.com/index.php/5/article/view/5818/5840
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0
dc.sourceWeb of Medicine: Journal of Medicine, Practice and Nursing ; Vol. 4 No. 1 (2026): WOM; 73-78
dc.source2938-3765
dc.subjectHIF-1α, placental dysfunction, preeclampsia, hypoxia-inducible factor, fetoplacental insufficiency, intrapartum fetal death, genetic polymorphism, endothelial dysfunction.
dc.titleTHE ROLE OF HYPOXIA-INDUCIBLE FACTOR HIF-1α IN THE PATHOGENESIS OF INTRAPARTUM FETAL DEATH IN PREECLAMPSIA
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typePeer-reviewed Article

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