FEATURES OF THE COGNITIVE STATUS IN WOMEN WITH IRON DEFICIENCY ANEMIA

Abstract

Goal. To give a comparative characteristic of the cognitive status in women, depending on the presence of iron deficiency anemia, to study the possibility of restoring the existing cognitive deficit against the background of correction of anemia with iron preparations. Materials and methods. The study included 40 women aged 18-44 years with an established diagnosis of mild and moderate iron deficiency anemia. A comprehensive clinical (laboratory and neuropsychological examination was performed using the MoCA test, the Gotland,Spielberger–Hanin scales, the asthenia assessment scale (MFI(20), initially (before the start of anemia therapy), after 12 and 24 weeks. The comparison was carried out with a control group of women without anemia.Results. During the examination of patients with mild and moderate iron deficiency anemia aged 18-44 years before the start of therapy, we revealed mild cognitive impairment, mainly of attention functions, fluency of speech, memory. Correction of anemia, normalization of hemoglobin, iron and serum ferritin against the background of anemia therapy with iron is associated with a decrease in the severity of cognitive impairment. Conclusions. The results of the study showed that ferrotherapy reliably restores the existing cognitive deficit in young patients diagnosed with mild and moderate iron deficiency anemia. However, with the restoration of hematological parameters, correction of cognitive deficits and improvement of the general well-being of patients, the asthenic component remains.