THE ROLE OF ANGIOGENIC (PDGF) AND ANGIOSTATIC (TSP-1) VASCULAR FACTORS IN THE DEVELOPMENT OF SYSTEMIC SCLERODERMA

dc.contributor.author	Abdakimova Baxtigul Ilhomiddin qizi
dc.date.accessioned	2025-12-29T12:46:33Z
dc.date.issued	2025-07-16
dc.description.abstract	Systemic scleroderma (SSc) is a severe autoimmune disease that leads to progressive fibrosis and vascular abnormalities. This study investigates the role of Platelet-Derived Growth Factor (PDGF) and Thrombospondin-1 (TSP-1) as key angiogenic and angiostatic factors in SSc progression. We examined 100 participants, including 80 patients with SSc and 20 healthy controls. Results show significantly elevated PDGF and TSP-1 levels in SSc patients, correlating with the degree of fibrosis and internal organ involvement.
dc.format	application/pdf
dc.identifier.uri	https://westerneuropeanstudies.com/index.php/3/article/view/2727
dc.identifier.uri	https://asianeducationindex.com/handle/123456789/19648
dc.language.iso	eng
dc.publisher	Western European Studies
dc.relation	https://westerneuropeanstudies.com/index.php/3/article/view/2727/1885
dc.rights	https://creativecommons.org/licenses/by-nc/4.0
dc.source	Western European Journal of Medicine and Medical Science; Vol. 3 No. 7 (2025): WEJMMS; 20-21
dc.source	2942-1918
dc.subject	Systemic scleroderma
dc.subject	PDGF
dc.subject	angiogenesis
dc.title	THE ROLE OF ANGIOGENIC (PDGF) AND ANGIOSTATIC (TSP-1) VASCULAR FACTORS IN THE DEVELOPMENT OF SYSTEMIC SCLERODERMA
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.type	Peer-reviewed Article

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