DETERMINATION OF THE CONTENT OF BIOLOGICALLY ACTIVE SUBSTANCES COMPOUNDS OF POLYPHENOLIC NATURE IN THE DRY EXTRACT "LEOFLOMIS"

Abstract

The article presents the data on the study of the polyphenolic composition of the dry extract "Leoflomis" obtained from the herb Regel's zopnik (Phlomis regelii M. Pop.) and Turkestan motherwort (Leonurus turkestanicus L.), which has a sedative effect. For the first time, a polyphenolic analysis was performed by HPLC in a dry extract of Leoflomis. As a result of the work carried out, it was found that the dry extract of Leoflomis contains rutin, hyperoside campferol, isoramnetin and hypolaetin. The largest number is routine (28.2946). Thus, the presence of the above-mentioned polyphenolic compounds in the dry extract indicates the prospects for the development of drugs with antioxidant and sedative activity and will be taken into account in subsequent studies to standardize the Leoflomis dry extract.