GENETIC STUDY OF THE TASTE OF PHENYLTHIOCARBAMIDE (PTC) TRAIT IN WASIT PROVINCE POPULATION

Abstract

The taste of PTC substance is one of the human traits that distinguishes people into tasters and non-tasters, controlled by a single gene (TAS2R38). The current study aimed to determine the genetic distribution of this trait in the community of Wasit Governorate, Iraq, and whether there is a deviation from the normal proportions of the trait. A sample of 500 students of both sexes from Wasit University students, aged between 19-25, were subjected to examination using PTC strips. The study showed that the number of tasters exceeds the number of non-tasters (345 and 155, respectively), and that females are more than males, with a significant difference (p.0.374). the homozygotes recessive (tt) which represented as q and dominants homozygote was represented as p in Hardy Weinberg equilibrium, and the allele frequency of q (t) was 0.211 and p (T) was 0.330 and according to Hardy Weinberg equilibrium, the heterozygotes are represented by the 2pq were (0.480).