A MATHEMATICAL MODEL OF LATENT TUBERCULOSIS INFECTION PROGRESSION TO LOCALIZED TUBERCULOSIS IN CHILDREN FROM HOUSEHOLD TB FOCI IN UZBEKISTAN
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Western European Studies
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Latent tuberculosis infection (LTBI) in children living in household TB contact settings remains a significant public health concern in high-incidence countries such as Uzbekistan. Although most infected children are asymptomatic, some progress to localized forms of tuberculosis, complicating both diagnosis and management. Objective: To develop a prognostic mathematical model for assessing the risk of progression from LTBI to localized tuberculosis in children exposed to active TB cases within household contact environments in Uzbekistan