COMORBIDITY IN PATIENTS WITH PEPTIC ULCER DISEASE

Abstract

The concept of comorbidity is a simultaneous lesion of two or more organs and systems of the body, proposed in 1970 by American physician A.R.Feinstein. Comorbidity affects the clinical course of the underlying disease, prognosis safety and effectiveness of treatment. [5,6]The problem of comorbidity is important for both science and practical health care. Comorbidity is distinguished by syndromal (transsyndromal) or nosologic (transnosologic) principle and somatic categorization. [1,2] This division is largely preliminary and inaccurate, because diseases can be associated with a single mechanism of pathogenesis, which is sometimes explained by the similarity of their clinical manifestations and complicates the differential diagnosis by nosology. There are several methods of comorbidity assessment, but there is no single universally recognized way of its measurement. [3,4] Therefore, we evaluated comorbidity by the number of systems and nosologies involved in the pathologic process.