Effect of Thymus vulgaris on liver tissue in dexamethasone treated female adult rat

Abstract

This experiment aimed to investigate the effect of Thymus vulgaris (T.vulgaris) on liver tissue treated by dexamethasone by long time administration. Twenty four adult female rats divided into 4 groups: first control group, second and third groups had subcutaneous injection with Dex 0.1mg/kg 3 times/week for 60 days, then third and fourth groups received 75 mg/kg of T.vulgaris orally for two weeks. At the end of the experiment liver tissues were collected via scarified the rat after end of experiment. Results of Liver histopathological of Dexa groups showed degenerative necrosis with inflammatory changes, all of these pathological alterations were ameliorate by T.vulgaris administration